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KMID : 0357920110450000066
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Korean Journal of Pathology
2011 Volume.45 No. 0 p.66 ~ p.69
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Brucella Prostatitis: A First Case Report Diagnosed in Korea
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Ryu Seong-Yeol
Kim Hyun-Ah
Park Ji-Young
Choe Mi-Sun
Kwon Kun-Young
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Abstract
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Brucellosis is a zoonosis caused by several species of Brucella. Brucellosis is usually an acute or sub-acute febrile illness that histologically develops granulomatous inflammation. Brucella prostatitis is a very rare complication and is usually accompanied by epididymo-orchitis. We now report a case of histologically proven granulomatous prostatitis due to Brucella without clinical evidence of epididymo-orchitis. A 61-year-old farmer presented with myalgia, low back pain, and fever. A needle biopsy of the prostate was performed due to symptoms of urinary frequency and high prostate specific antigen levels (17.3 ng/mL). Histologically, the prostate showed granulomatous inflammation without caseous necrosis. Polymerase chain reaction (PCR) studies of blood and prostatic tissue for Brucella were positive, while a PCR study for Mycobacterium tuberculosis was negative. The patient was treated with doxycycline and rifampin. A possibility of Brucella pros-tatitis should be considered in the differential diagnosis of granulomatous prostatitis or prostatitis of unknown origin associated with or without epididymo-orchitis.
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KEYWORD
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Brucella, Prostatitis, Granuloma
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